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Senior Principal Scientist, Bispecifics & Antibody Engineering

Regeneron • Tarrytown, NY, US • published 2026-11-05 06:59:20.725124

Description

* Team:Research \& Preclinical Development * Location:Tarrytown * Req ID:R51999 * Contract:Full time * Work Pattern:Onsite **The role** ------------ **Build our future together:** At Regeneron, we use science and innovation to develop life\-changing medicines for people with serious diseases. We are seeking a Senior Principal Scientist to lead a small team within our Bispecific Antibodies group, using structural insight to design, engineer, and optimize next\-generation bispecific and multispecific antibody therapeutics. In this role, you will integrate structural data with AI/ML\-enabled design and high\-throughput, automated experimental validation, co\-championing programs with biology leads from concept to IND. This position offers the opportunity to contribute to a fast\-growing, science\-driven organization making a meaningful difference to patients worldwide. **When \& where:** * Location: Tarrytown, NY * Work model/flexibility: Onsite **Discover your role:** * Set molecular design strategy for bispecific and multispecific antibodies based on target biology, structure, and mechanism of action * Lead structure\-guided design of novel formats, including binding\-arm selection,...

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